exome sequencing GEMINI load error

I am currently doing my project work on Exome sequencing and is using the following tutorial (Exome sequencing data analysis for diagnosing a genetic disease). I have an error in GEMINI load tool. It is showing that the VCF format is unavailable(SNPEff eff). Please look into the problem and help me with it. Thank you

Hi @Thara_Dharanidhar
not quite sure what we are seeing in those screenshots.
Apparently, you’ve run the tool already and have produced a gemini.sqlite dataset with it?
Anyway, the reason why the Vcf dataset is not offered in the select box is likely that you haven’t set a format/dbkey on it. Click on the pencil icon on your dataset and set the dbkey to hg19.

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Hi @wm75
I did exactly what you told but i am not getting the output. I set the dbkey as hg19 but no result.Can u suggest alternative tool instead of GEMINI load.

I’m sorry, but I don’t understand what the issue is. You have obtained a GEMINI load dataset and its state is green. Everything looks good and you can just continue with the tutorial, can’t you?

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GEMINI load tool is working and its state is also green but I am unable to view the output as some file is getting downloaded every time I click the view option. What kind of data will be obtained from GEMINI load tool as you can see my screenshot showing that (loading chunk 1 , loading chunk 2…) So the data will look like this or in some other format. Please help me out.

This file is getting downloaded whenever I click the view data . When I click the file this message appears “file cannot be viewed”.

Yes, the GEMINI load tool produces a GEMINI database, which is not intended to be viewed, but queried. Please follow the tutorial, which explains a few ways how you can do that.
These tutorials: Identification of somatic and germline variants from tumor and normal sample pairs and Calling variants in diploid systems demonstrate more options.
Think of the GEMINI database as a computer-friendly version of a VCF. You can’t read it, but queries are very efficient. The GEMINI load tool is essentially the converter that takes VCF and produces the database format.

Thank you so much for your help.