Kraken2 databases

Hi, I’m curious the differences between the standard and minikraken2 databases for the Kraken2 tool. Is it just that minikraken2 is a smaller database, and therefore runs faster?
Would there be other reasons to use one over the other? Thank you!

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Hi @scarletbliss

Short answer: Yes

Memory utilization is also a factor. Full-sized Kraken reference databases (indexes) requires more resources – both to create and map against. The full-size index will be more complete content-wise – and that is the trade off (performance versus content).

Reference: https://ccb.jhu.edu/software/kraken2/ >> https://github.com/DerrickWood/kraken2/wiki/Manual#kraken-2-databases

Thanks!