problem of not installing dependencies in galaxy 19.05

[uWSGIWorker2Core0] Removing failed conda install of [CondaTarget[picard,version=2.18.2], CondaTarget[r-base,version=3.4.1]]
[uWSGIWorker2Core0] Removing failed conda install of r-base, version ‘3.4.1’
[uWSGIWorker2Core0] Removing failed conda install of picard, version ‘None’
galaxy.tools.deps.resolvers.conda DEBUG 2019-12-07 09:07:52,653 [p:72819,w:2,m:0]
[uWSGIWorker2Core0] Removing failed conda install of r-base, version ‘None’
galaxy.tools.deps DEBUG 2019-12-07 09:07:52,703 [p:72819,w:2,m:0] [uWSGIWorker2Core0] Dependency picard not found.
galaxy.tools.deps DEBUG 2019-12-07 09:07:52,703 [p:72819,w:2,m:0] [uWSGIWorker2Core0] Dependency r-base not found.
galaxy.tools.deps DEBUG 2019-12-07 09:07:52,703 [p:72819,w:2,m:0] [uWSGIWorker2Core0] Dependency picard not found.
galaxy.tools.deps DEBUG 2019-12-07 09:07:52,703 [p:72819,w:2,m:0] [uWSGIWorker2Core0] Dependency r-base not found.
galaxy.tools.deps DEBUG 2019-12-07 09:07:52,703 [p:72819,w:2,m:0] [uWSGIWorker2Core0] Dependency picard not found.
galaxy.tools.deps DEBUG 2019-12-07 09:07:52,703 [p:72819,w:2,m:0] [uWSGIWorker2Core0] Dependency r-base not found.
galaxy.tools.deps DEBUG 2019-12-07 09:07:52,704 [p:72819,w:2,m:0] [uWSGIWorker2Core0] Dependency picard not found.
galaxy.tools.deps DEBUG 2019-12-07 09:07:52,704 [p:72819,w:2,m:0] [uWSGIWorker2Core0] Dependency r-base not found.
galaxy.tools.deps DEBUG 2019-12-07 09:07:52,704 [p:72819,w:2,m:0] [uWSGIWorker2Core0] Dependency picard not found.
galaxy.tools.deps DEBUG 2019-12-07 09:07:52,704 [p:72819,w:2,m:0] [uWSGIWorker2Core0] Dependency r-base not found.
galaxy.tools.deps DEBUG 2019-12-07 09:07:52,704 [p:72819,w:2,m:0] [uWSGIWorker2Core0] Dependency biom-format not found.
galaxy.tools.deps DEBUG 2019-12-07 09:07:52,704 [p:72819,w:2,m:0] [uWSGIWorker2Core0] Dependency biom-format not found.

I don’t know if what I have encountered is the same but going in and deleting the relevant folder from tool-deps/_conda/envs/ and restarting the dependency install has worked to fix failed installs.

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After doing what you mentioned and trying to install dependencies the state of dependencies does not change.
I see a lot of Dependency python not found. errors in galaxy log.

I have not experienced that issue myself.
I might try and rename the _conda folder and restart galaxy. Hopefully it will regenerate the conda install automatically.