# RNA-STAR and hg38 GTF reference annotation

**URL:** <https://help.galaxyproject.org/t/rna-star-and-hg38-gtf-reference-annotation/749>\
**Category:** usegalaxy.org support\
**Tags:** troubleshooting, transcriptomics, reference-annotation, rna\_star\
**Created:** [March 6, 2019, 9:31pm UTC](https://help.galaxyproject.org/t/rna-star-and-hg38-gtf-reference-annotation/749 "2019-03-06T21:31:46Z")\
**Posts on this page:** 1\
**Showing post:** 7

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**Author:** ![jennaj](https://sea2.discourse-cdn.com/flex020/user_avatar/help.galaxyproject.org/jennaj/32/27_2.png) [@jennaj](https://help.galaxyproject.org/u/jennaj)\
**Post date:** [October 13, 2020, 6:38pm UTC](https://help.galaxyproject.org/t/rna-star-and-hg38-gtf-reference-annotation/749/7 "2020-10-13T18:38:55Z")

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Hi @aaak

This may be the root problem (not all jobs that were executing when the downtime started ended gracefully). Please see: [UseGalaxy.org scheduled maintenance downtime October 13, 2020 – status and updates](https://help.galaxyproject.org/t/usegalaxy-org-scheduled-maintenance-downtime-october-13-2020-status-and-updates/4605)

Once the server is back up, try a rerun. If you are still having problems: Please send in a bug report, include a link to this topic in the comments, then post back here so we know when to look for it.

This _could_ be an actual content or setting issue we can help with. But, error messages can be unreliable when a job crashes due to problematic inputs (much depends on whether the original author anticipated and trapped specific problematic use cases). Plus, given the current downtime, I wouldn’t trust any of that quite yet. I doubt this is a tool configuration problem but we can check that with your rerun sent in as a bug report. (Details: [https://www.google.com/search?q=star%20"is%20too%20large%20for%20the%20genome%20size"](https://www.google.com/search?q=star%20%22is%20too%20large%20for%20the%20genome%20size%22)).

Thanks!

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_[View the full topic](https://help.galaxyproject.org/t/rna-star-and-hg38-gtf-reference-annotation/749)._
