Error in SnpEff version

I used Snpeff on the output of VCFfilter tool at the version 5.2+galaxy1 and the result showed an error.
The AI error analysis displayed that it may be due to the database file format changed between the 4.x and 5.x families, so a 5.x program cannot load a 4.x database.
"The error message therefore stops the tool with:
Database version : ‘4.3’
Program version : ‘5.2’
Compatible versions : ‘[5.2, 5.0, 5.1]’
"


And to fix it, I had to make sure the required SnpEff version is 5.2. I would prefer to receive any advice before running the tool once again. Kindly suggest.

The ai response may be true or not, but to debug some concrete info would be a lot more helpful:

  • which snpeff tool (tool id) have you been running
  • what was the complete error message
  • how did you install the sneff genome and make it accessible from Galaxy

Thanks for sharing those details.

I was able to reproduce this with SnpEff eff 5.2 on Galaxy Europe.

The reason is that we installed hg19 and hg38 genomes for v5.2 this week and those are clashing with the previously installed same genomes for v4.3.

We’re working on fixing this.

The issue is fixed on Galaxy Europe.

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Thank you very much.