Does anyone know if the Jan 1 2020 deprecation of Python 2.7 will effect locally installed Galaxy? Also, does the software upgrade to Catalina have any bugs?
Not until Apple stop supporting Python 2.7, assuming you are using macOS.
Any way it should be pretty easy to port your local Galaxy to Python 3 by replacing the virtual environment that Galaxy uses (by default
.venv) with a new one created with
virtualenv -p python3 .venv .